It is chiefly valuable for the alloys it forms, especially many superalloys, and particularly stainless steel. It is magnetic, and is very frequently accompanied by cobalt, both being found in meteoric iron. It is clear that in common with massive forms of chromium, aluminium and titanium metal that nickel is very slow to react with air, but it is a very reactive element.īecause of its permanence in air and its inertness to oxidation, it is used in coins, for plating iron, brass, etc., for chemical apparatus, and in certain alloys, such as German silver. It occurs most usually in combination with sulfur and iron in pentlandite, with sulfur in millerite, with arsenic in the mineral nickeline, and with arsenic and sulfur in nickel glance. It belongs to the transition metals, and is hard and ductile. Nickel is a silvery white metal that takes on a high polish. Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g.Lustrous, metallic and silvery with a gold tinge Standard atomic weight Tumorigenic - Carcinogenic by RTECS criteria Tumorigenic - tumors at site of application Tumorigenic - neoplastic by RTECS criteria Musculoskeletal - tumors Tumorigenic - tumors at site of application Tumorigenic - equivocal tumorigenic agent by RTECS criteria Musculoskeletal - tumors Tumorigenic - tumors at site of application Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Lungs, Thorax, or Respiration - bronchiogenic carcinoma Tumorigenic - neoplastic by RTECS criteria Reproductive - Tumorigenic effects - uterine tumors Tumorigenic - tumors at site of application Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Reproductive - Tumorigenic effects - uterine tumors Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application Tumorigenic - Carcinogenic by RTECS criteria Musculoskeletal - tumors Tumorigenic - tumors at site of application Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application Lungs, Thorax, or Respiration - other changes Lungs, Thorax, or Respiration - other changes Biochemical - Metabolism (Intermediary) - lipids including transport Lungs, Thorax, or Respiration - other changes Lungs, Thorax, or Respiration - changes in lung weight Biochemical - Metabolism (Intermediary) - lipids including transport TP, bilirubin, cholesterol) Blood - changes in erythrocyte (RBC) count Liver - liver function tests impaired Blood - changes in serum composition (e.g. TCLo - Lowest published toxic concentration Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis) Related to Chronic Data - death Vascular - regional or general arteriolar or venous dilation Liver - other changes Blood - other changesīehavioral - somnolence (general depressed activity) Behavioral - fluid intake Kidney, Ureter, Bladder - proteinuria Details of toxic effects not reported other than lethal dose value
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